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The LITFL Clinical Case Collection includes over 250 Q&A style clinical cases to assist ‘ Just-in-Time Learning ‘ and ‘ Life-Long Learning ‘. Cases are categorized by specialty and can be interrogated by keyword from the Clinical Case searchable database.

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Global health case reports.

These are case reports that focus on the causes of ill health, the social determinants of health and access to healthcare services, prevailing local and national issues that affect health and wellbeing, and the challenges in providing care to vulnerable populations or with limited resources.

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24 January 2024

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Latest Articles

22 December 2024

Ophthalmology :

20 December 2024

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Acute hemolytic crisis complicated with ischemic cardiac injury and methemoglobinaemia following ingestion of naphthalene: a case report

Naphthalene is an aromatic hydrocarbon that potentially produces methemoglobinaemia but rarely causes hemolysis, especially in children with underlying glucose-6-phosphate dehydrogenase deficiency. Although in...

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Applying auricular magnetic therapy to decrease blood glucose levels and promote the healing of gangrene in diabetes patients: a case report

Magnetic therapy has demonstrated beneficial effects for reducing pain, nausea, neuropathy, and various other health concerns in the human body. To our knowledge, limited research has documented the use of aur...

Liver resection for breast cancer-related liver metastases: a case report

Breast cancer liver metastasis presents a significant challenge in clinical oncology, with limited treatment options and poor prognosis. This case series study explores the extended survival achieved in breast...

Using right colon interposition in patients with caustic ingestion, an introduction of a new surgical technique for post-gastrectomy reconstruction: a case series

Corrosive substance ingestion is rare but can cause severe injury, especially to the upper gastrointestinal tract, and can be a potentially fatal event. Various surgical procedures have been advocated for gast...

Renal cell carcinoma metastasis to the thyroid gland: a case report

In this article, we report a case of renal cell carcinoma metastasis to the thyroid gland. Occult lesions of the thyroid were treated with a thyroidectomy. The case history presented below describes the patien...

Probable collagenous gastritis via Epstein–Barr virus reactivation in the setting of coronavirus disease 2019: a case report

Recent biomedical research has shown the unusual, multisystem effects of coronavirus disease 2019 in humans. One specific sequela of a primary severe acute respiratory syndrome coronavirus 2 infection is the r...

Abdominal kaposiform hemangioendothelioma presenting as volvulus and recurring intestinal obstruction in a neonate: a case report

Kaposiform hemangioendothelioma is a rare vascular tumor primarily occurring in infants and children. The most common sites for kaposiform hemangioendothelioma are extremities, with very few cases of abdominal...

Giant prolactinoma with progressive cranial settling and central herniation: a case report

Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical interventio...

Successful treatment of tumor lysis syndrome associated with hepatic artery infusion chemotherapy in a patient with hepatocellular carcinoma: a case report

Tumor lysis syndrome is a life-threatening complication in the treatment of cancer. However, it rarely occurs in solid tumors, especially in hepatocellular carcinoma.

Spinal schwannoma presenting with intraspinal hematoma: a case report and review of the literature

Spinal schwannomas presenting with an intraspinal hematoma or subarachnoid hemorrhage are extremely rare, and patients often have severe spinal cord compression symptoms. However, the mechanism underlying the ...

Postorgasmic illness syndrome benefiting from omalizumab and antidepressant: a case report

Postorgasmic illness syndrome is characterized by flu, rhinitis, conjunctivitis, loss of appetite, muscle weakness, and fatigue after ejaculation, lasting 2–7 days. The multidisciplinary treatment approach, in...

Polyarteritis nodosa presenting with severe upper gastrointestinal bleeding: a case report

Polyarteritis nodosa is a relatively uncommon type of systemic necrotizing vasculitis that primarily affects medium-sized arteries. While gastrointestinal involvement is known in polyarteritis nodosa, heavy ga...

“Bone marrow–liver–spleen-type diffuse large B-cell lymphoma” presenting with cold autoimmune hemolytic anemia: a case report

Primary bone marrow diffuse large B-cell lymphoma is a rare clinical entity, and the “bone marrow–liver–spleen” type of diffuse large B-cell lymphoma is rarer, with only a few published cases in literature. Th...

Exponential decline, ceiling effect, downregulation, and T-cell response in immunoglobulin G antibody levels after messenger RNA vaccine boosters: a case report

Vaccine protection against severe acute respiratory syndrome coronavirus 2 infection reduces gradually over time, requiring administration of updated boosters. However, long-term immune response following up t...

Atypical Kawasaki disease with giant coronary artery aneurysms in a 2-month-old boy: a case report

Kawasaki disease is an acute inflammatory disorder primarily affecting medium-sized blood vessels, especially in infants and young children under 5 years old, characterized by inflammation of the arterial wall...

Acute kidney injury and tacrolimus toxicity in a kidney transplant recipient treated with nirmaltrevir/ritonavir: a case report

Kidney transplant recipients with severe acute respiratory syndrome-coronavirus-2 infection have an increased risk of severe disease and mortality. Nirmaltrevir/ritonavir (Paxlovid) is an effective oral diseas...

AIRE mutation in an elderly Caroli’s patient with cholangitis and sepsis: a case report

Caroli’s disease, an autosomal recessive, hereditary-related disorder, is a rare disease, in which the diagnosis is based primarily on medical imaging and pathophysiological examinations. It is characterized b...

Intermuscular hydatid cyst in the thigh musculature: a case report

Echinococcus granulosus , a tapeworm, is responsible for causing hydatid disease. Hydatid cysts rarely affect the musculoskeletal system, occurring in less than 5% of cases. This case report presents the clinical ...

Adult-onset hypophosphatasia diagnosed after consecutive tooth loss during orthodontic treatment: a case report

Adult hypophosphatasia is an uncommon inherited disorder of mineral homeostasis affecting bone. It arises from mutations within the Alkaline Phosphatase, Biomineralization Associated ( ALPL ) gene, which encodes ti...

Mass-forming type 2 autoimmune pancreatitis with upstream dilatation of the main pancreatic duct dilatation: a case report

Type 2 autoimmune pancreatitis is characterized by multiple or segmental strictures of the main pancreatic duct without upstream dilatation. We encountered a case of mass-forming type 2 autoimmune pancreatitis...

Management of patient with acute lymphocytic myocarditis and congenital long QT syndrome presenting with electrical storm and incessant Torsade de Pointes: a case report

This case highlights the management of concomitant acute myocarditis and congenital long QT syndrome with electrical storm and incessant Torsade de Pointes.

Pleural carcinoid diagnosed via video-assisted thoracoscopy biopsies in a patient with recurrent unilateral pleural effusion at St. Francis hospital Nsambya: a case report

Pulmonary carcinoids are rare neuroendocrine tumors accounting for less than 1% of all lung cancers. They are classified into two subcategories; typical and atypical carcinoids with the latter tending to grow ...

Atypical presentation of oral Burkitt lymphoma in an adult: a case report

Burkitt lymphoma is an aggressive form of non-Hodgkin B cell lymphoma. Oral lesions often are a component of the disseminated disease process that may involve regional lymph nodes or may at times represent the...

Complicated iatrogenic Cushing’s syndrome induced by topical clobetasol propionate in a child with psoriasis: a case report and review of the literature

Long-term use of oral or parenteral corticosteroids is the most common cause of hypothalamic–pituitary–adrenal axis suppression and iatrogenic Cushing’s syndrome. Still, iatrogenic Cushing’s syndrome occurs ra...

Genotypic and phenotypic analysis of an oculocutaneous albinism patient: a case report and review of the literature

Oculocutaneous albinism is a rare autosomal recessive disorder caused by congenital melanin deficiency, resulting in hypopigmentation of the eyes, hair, and skin. This study included a Chinese family with an o...

An intracranial odyssey: pediatric ganglioneuroma arising from the trigeminal ganglion: a case report and review of the literature

Ganglioneuroma represents an uncommon benign tumor arising from the sympathetic nerves, and its development from the fifth nerve is an infrequent entity. Few ganglioneuromas arising from the fifth nerve have b...

Yellow nail syndrome linked to a mediastinal lipoma: a case report

Yellow nail syndrome is characterized by a yellow discoloration of the nails, respiratory symptoms, and lymphedema. It was first described in 1964 and has an estimated prevalence of less than 1:1.000.000. Desp...

Targeting scapular muscles with facilitatory movement patterns to improve upper extremity function in gangliocapsular stroke: a case report

Gangliocapsular stroke is a specific type of hemorrhagic stroke that primarily affects the basal ganglia and internal capsule due to rupture of the lenticulostriate perforating arteries. Patients afflicted wit...

Conjoined twin at abdomen: twin A anencephaly and face presentation with twin B cephalic presentation: a case report and review of the literature

Conjoined twins are described as having been physically fused during pregnancy and delivery. They share some vital organs, such as the heart, lungs, liver, abdomen, etc. The article aims to present a unique di...

First-line endocrine therapy combined with CDK 4/6 inhibitor in disseminated carcinomatosis of bone marrow (DCBM) luminal breast cancer: a case report

Metastatic breast cancer especially in disseminated carcinomatosis of bone marrow (DCBM) poses a life-threatening risk, often requiring systemic chemotherapy. This situation lacks a cure, emphasizing symptom r...

Deep vein thrombosis and aneurysm co-occurrence: a case report and review of the literature

The co-occurrence of deep vein thrombosis with vascular aneurysms, whether venous or arterial, seems to be uncommon. This case report details a patient who experienced an isolated rupture of the right common i...

Synchronous occurrence of papillary thyroid carcinoma and solitary fibrous tumor of the thyroid: a case report

Solitary fibrous tumors (SFT) are ubiquitous mesenchymal neoplasms of intermediate malignant potential. SFTs of the head and neck are rare, representing less than 0.1% of all SFTs. Solitary fibrous tumors of t...

Complications of delayed diagnosis and challenges: successfully managed SPTB gene variant hereditary spherocytosis with hepatocellular jaundice—a case report

Hereditary spherocytosis is a rare genetic disorder of the red blood cell membrane that is characterized by anemia, jaundice, and splenomegaly; however, in the absence of family history and with unusual clinic...

Synovial chondromatosis, a cause of hip pain: a case report

Synovial chondromatosis is a proliferative disease of the synovium associated with cartilage metaplasia that causes localized joint pain and affects its function.

Minimally invasive management of intramural pregnancy using ultrasound combined with laparoscopy -based learning experience from a low-middle income country: a case report and review of the literature

Intramural pregnancy is a very rare type of ectopic pregnancy, which is surrounded by uterine myometrium layer and separates from endometrium. To our knowledge, this abnormal location site of ectopic pregnancy...

Partial vitreous occlusion of Ahmed glaucoma valve implant with controlled intraocular pressure: a case report

The Ahmed glaucoma valve implant is effective in reducing intraocular pressure, yet it poses a risk of complications such as vitreous occlusion of the tube, potentially resulting in elevated intraocular pressu...

Severe Xanthogranulomatous prostatitis mimicking prostate cancer: a case report

Xanthogranulomatous prostatitis is a rare, noncancerous inflammatory condition of the prostate that clinically resembles prostatic carcinoma, necessitating a pathological examination for accurate diagnosis.

Acute myocardial infarction presenting as headache: a case report

The diagnosis of acute myocardial infarction is straightforward when it presents with typical symptoms. However, some patients can be asymptomatic, and some can present with atypical symptoms.

Relations between daily stressful events, exertion, heart rate variability, and thoracolumbar fascia deformability: a case report

The posture of performance-oriented sport climbers adapts in a way that likely promotes the development of low back pain. The thoracolumbar fascia, while also contributing to performance, seems to be involved ...

External auditory canal osteoma with coexisting canal wall cholesteatoma: a case report and review of literature

Though rare, benign lesions that usually do not necessitate active intervention, osteomas of the external auditory canal, can be troublesome when they start to produce mass effect and severe obstruction to the...

Post-radical hysterectomy ovarian torsion—A gynecological emergency: a case series

Ovarian torsion is a surgical emergency whereby the ovary twists, or torts, on its ligamentous support and potentially compromises vascular supply to both the ovary and Fallopian tube. It accounts for 2–3% of ...

Tracheal stenosis misdiagnosed as asthma: a case report

Tracheal stenosis is a known complication following intubation. However, owing to its delayed presentation and symptoms of progressive wheezing and respiratory difficulty, it is often misdiagnosed as asthma.

Application of bronchoalveolar lavage fluid cytomorphology in diagnosing Nocardia otitidiscaviarum : a case report

Nocardiosis is a rare infectious disease, which is frequently underdiagnosed because of the distinct bacterial shape of the causative agent and its developmental history. The morphological analysis of bronchoa...

Ventricular premature beats in a pregnant woman originating from trabeculae carneae in the right ventricle treated with radiofrequency ablation without X-ray guidance: a case report

Premature ventricular beats increase the cardiac load in pregnant women, leading to symptoms, such as palpitations. In severe instances, they may reduce placental perfusion, potentially causing intrauterine di...

Modified abdominal radical trachelectomy used to spare fertility during surgery for early-stage cervical cancer: a case report

Cervical cancer is the fourth most common malignant tumor in childbearing-age women. To date, cervical resection and fertility-sparing surgery are the trends in the era of minimally invasive management. Howeve...

Post-traumatic intraosseous sheath development of the extensor carpi radials brevis tendon: a case report

Complications from closed treatment in children are rare but can include growth disturbances and deformities. This case report presents a unique, post-traumatic growth deformity in the distal radius, where the...

A case of giant fronto-ethmoidal osteoma (45 × 42 mm) with intracranial and orbital extension: a case report

Osteomas are the most common benign tumors of the sinonasal region. Often asymptomatic, they are frequently discovered incidentally during imaging studies conducted for unrelated conditions. Osteomas typically...

Syringocystadenocarcinoma of the perianal region: a case report

Syringocystadenocarcinoma papilliferum is an extremely rare malignant adnexal tumor that typically arises from a papilliferous syringocystadenoma (World Health Organization classification of skin tumors, 2018....

An example of cytisine overdose with no consequent side-effects: a case report

Cytisine is an alkaloid that is molecularly similar to nicotine and it is commonly used to treat smoking cessation. While it is considered a reasonably safe treatment option, cytisine intoxication in humans ex...

Late relapse of anti- N -methyl- d -aspartate receptor (NMDAR) encephalitis: a case report

Anti- N -methyl- d -aspartate receptor encephalitis is a sporadic autoimmune disorder of the brain that presents in a variety of neuropsychiatric manifestations, including seizures, psychosis, and alterations in beha...

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Journal of Medical Case Reports

ISSN: 1752-1947

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